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	<title>News Vulture &#187; adenocarcinoma</title>
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	<link>http://www.newsvulture.com</link>
	<description>Focusing on Corruption in India. Bringing out the profiles most crooked in India.</description>
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		<title>Alcohol flush signals cancer risk</title>
		<link>http://www.newsvulture.com/2009/03/24/alcohol-flush-signals-cancer-risk/</link>
		<comments>http://www.newsvulture.com/2009/03/24/alcohol-flush-signals-cancer-risk/#comments</comments>
		<pubDate>Tue, 24 Mar 2009 09:35:50 +0000</pubDate>
		<dc:creator>Sunbird</dc:creator>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[adenocarcinoma]]></category>
		<category><![CDATA[Alcohol]]></category>
		<category><![CDATA[cancer risk]]></category>
		<category><![CDATA[carcinoma]]></category>
		<category><![CDATA[Dr. Akira Yokoyama]]></category>
		<category><![CDATA[esophagael risk]]></category>
		<category><![CDATA[Japan]]></category>
		<category><![CDATA[Kurihama Alcohol Center]]></category>
		<category><![CDATA[Risk factor]]></category>

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		<description><![CDATA[Alcohol is a known risk factor for a variety of cancers, including esophageal, and heavier drinking is considered riskier than light drinking. Lots of people turn slightly red if they imbibe too much. At issue here is facial flushing from a small amount of alcohol. It&#8217;s due to a deficiency in an enzyme that helps metabolize alcohol, called ALDH2. People with a severe deficiency of the enzyme usually don&#8217;t drink because it makes them feel too bad; in addition to flushing they feel nausea and a rapid heartbeat. But people with a partial deficiency — they inherited one bad copy of the enzyme-producing gene instead of two — may put up with the flushing. A series of studies by Dr. Akira Yokoyama of Japan&#8217;s Kurihama Alcohol Center found that those people are six to 10 times more likely to develop esophageal cancer than people who drink a comparable amount but aren&#8217;t enzyme-deficient. Without enough of that enzyme, alcohol breaks down into a DNA-damaging chemical similar to formaldehyde but it doesn&#8217;t go the next step and turn into yet another chemical that&#8217;s non-toxic, said Brooks. Don&#8217;t drink, and the flushers aren&#8217;t at increased risk. Esophageal cancer is fairly rare, but it&#8217;s [...]]]></description>
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